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Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients

RECRUITINGPhase 4Sponsored by University of Florida
Actively Recruiting
PhasePhase 4
SponsorUniversity of Florida
Started2020-11-10
Est. completion2026-06-18
Eligibility
Age18 Years – 99 Years
SexFEMALE
Healthy vol.Accepted
Locations1 site

Summary

Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in Intraocular Pressure (IOP) in robotic case in steep Trendelenburg with IV anesthetics (TIVA). We want to quantify the degree of change in Intraocular Pressure (IOP) in female patients undergoing robotic procedures for cancer. We want to detect the difference in increase of pressure with total IV anesthesia versus conventional balanced anesthesia

Eligibility

Age: 18 Years – 99 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Females ≥ eighteen years of age
* Written informed consent obtained from the subject and the subject agrees to comply with all the study-related procedures
* Subjects must be planning to receive robotic surgery for gynecological cancer or high suspicion of cancer (these subject will be withdrawn if it his proven they don't have cancer)
* Subjects must be cleared for surgery by the pre-anesthesia clinic
* All robotic GYN cancer patients 18 years of age and older with any preexisting medical conditions that are deemed ready for surgery by the pre anesthesia clinic

Exclusion Criteria:

* Known increased intraocular pressure, prior eye surgery within a month, eye conditions where the ophthalmologist would not allow an intra ocular pressure measurement
* Subjects with a previous treatment of diagnosis of increased intraocular pressure
* Subjects who have undergone eye surgery in the 30 days prior to consent
* Subjects for whom an ophthalmologist has determined cannot undergo intraocular pressure measurement

Conditions3

CancerIntraocular PressureOncology

Locations1 site

University of Florida
Gainesville, Florida, 32610
Sonia Mehta, MD352-273-7094sdeshmukh@anest.ufl.edu

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