Contribution of Computed Tomography and Cardiac-MRI in Atrial Fibrillation Ablation

Summary

Atrial fibrillation ablation (AF) is a standard interventional treatment for patients with symptomatic AF refractory to medical treatment. The known predictive factors for the success of the procedure remain insufficient to predict the probabilities of success and to appropriately select the patients who could benefit the most from this procedure. Left atrium imaging by MRI or CT may be able to identify AF substrate. However data are lacking about the practical impact of these techniques in routine practice to predict AF ablation outcome. The "CT-AF" study is a prospective, interventional, multicenter cohort study. The main objective of this study is to evaluate the prognostic value of a new automated measurement technique for intra-myocardial atrial fat measurement in cardiac CT and the measurement of global left atrial strain in MRI in patients who are candidates for first AF ablation. The main outcome will be the relationship between the relative volume of left atrial fat measured with CT and total left atrial strain in MRI and recurrence of AF at 1 year after the ablation procedure (blanking period of 3 months post ablation excluded).

Eligibility

Inclusion Criteria:

* Patient in whom radiofrequency AF ablation is scheduled within the next 6 months.
* age ≥18 years
* Patient affiliated to a social security scheme
* Patient informed and given written consent for participation in the study.

Exclusion Criteria:

* Refusal to participate in the study
* Patient who has already benefited from an AF ablation procedure
* Patient for whom an AF ablation procedure by cryoablation system is planned
* Scanner or MRI pre-inclusion not exploitable
* Presence of an implantable cardiac prosthesis of pacemaker type or defibrillator
* Claustrophobia
* Iodinated / gadolinium contrast medium allergy
* Chronic renal failure with clearance \<30ml / min
* Follow-up visits not possible
* Pregnancy in progress
* Patients unable to sign consent
* Minors and adults protected under legal protection (tutorship or guardianship)
* Period of exclusion from a research study

Conditions2

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