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SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training

RECRUITINGN/ASponsored by University of Liege
Actively Recruiting
PhaseN/A
SponsorUniversity of Liege
Started2020-09-01
Est. completion2028-09-01
Eligibility
Age18 Years – 65 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04395937

Summary

The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.

Eligibility

Age: 18 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

* asthmatic patient
* aged 18- 65 years
* ACQ \> 1.5
* stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene

Exclusion Criteria:

* IMC \> 35
* severe osteoarthritis of the knees and hips
* unstable angor
* Severe uncontrolled hypertension

Conditions2

AsthmaChronic Asthma

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