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Outcomes Associated With Suicidality in Inpatients With Symptoms of Depression (OASIS-D)

RECRUITINGSponsored by Charite University, Berlin, Germany
Actively Recruiting
SponsorCharite University, Berlin, Germany
Started2020-08-01
Est. completion2024-12-31
Eligibility
Age18 Years – 75 Years
Healthy vol.Accepted

Summary

This 6-month, naturalistic cohort study examines male and female inpatients aged 18 to 75 years i) with any form of unipolar depressive episode (cohort 1); ii) clinical diagnosis of a moderate or severe unipolar depressive episode and suicidal tendencies who agree to participate in a prospective study (cohort 2); and moderate or severe unipolar depressive episodes validated by research interviews and and suicidal tendencies that persist for at least 48 hours after admission who are followed up for 6 months (cohort 3).

Eligibility

Age: 18 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

For Population 1

1.any form of unipolar depressive episode

For Population 2

1. clinical diagnosis of a moderate or severe unipolar depressive episode
2. clinically diagnosed suicidal tendencies that persist for at least 48 hours after admission to hospital
3. Written consent to participate in the study

For Population 3

1. Diagnosis of a moderate or severe unipolar depressive disorder through the structured research interview "Mini International Neuropsychiatric Interview" (M.I.N.I.)
2. Suicidality with a value \> / = 1 for item 2 (passive suicidality) OR item 3 (active suicidality) based on the research interview "Sheehan Suicidality Tracking Scale" (S-STS)
3. Written consent to participate in the study

Exclusion Criteria:

* Patients younger than 18 years or older than 75 years
* No clinical diagnosis of a depressive episode
* Depressive episode in the context of a bipolar disorder- secondary depression as a result of physical illness or substance use
* severe physical symptoms of disease that make participation in the study impossible
* Pregnancy
* not being able to understand the study processes
* incapable of giving informed consent
* no authorization to give consent due to (limited) incapacity

Conditions6

DepressionDepression ModerateDepression SevereSuicidal IdeationSuicidal and Self-injurious BehaviorSuicide, Attempted

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