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Validation of Continuous Transcutaneous Carbon Dioxide Monitoring in VA-ECMO Patients

RECRUITINGSponsored by Medical University of Vienna
Actively Recruiting
SponsorMedical University of Vienna
Started2019-11-18
Est. completion2025-01-31
Eligibility
Age18 Years – 90 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04445909

Summary

Carbon dioxide in patients on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is eliminated via respirator as well as via the oxygenator's membrane of the ECMO machine. Consequently, monitoring of end-tidal carbon dioxide tensions is limited, which can result in marked swings towards non-physiological values. Hyper- and hypocapnia, however, can have detrimental effects on organ perfusion in a great number of patients supported with VA-ECMO. Continuous, rapidly applicable monitoring of reliable carbon dioxide measures would therefore be extremely helpful to prevent harmful deviations from the norm. The investigators therefore try to assess the accuracy and the precision of continuously measured non-invasive transcutaneous carbon dioxide partial pressures when compared with tensions determined by blood gas analysis.

Eligibility

Age: 18 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* Low cardiac output requiring VA-ECMO support.

Exclusion Criteria:

* Age \< 18 years

Conditions2

Carbon DioxideHeart Disease

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