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Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

RECRUITINGN/ASponsored by Heart and Brain Research Group, Germany
Actively Recruiting
PhaseN/A
SponsorHeart and Brain Research Group, Germany
Started2020-08-14
Est. completion2026-03
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04493996

Summary

Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation
* A sufficiently good knowledge of German is necessary as cognitive training and neuropsychological tests are language-dependent

Exclusion Criteria:

* History of stroke and preexisting psychiatric or neurological disorders that may impair the neuropsychological performance

Conditions4

Heart DiseasePostoperative Cognitive DeclinePostoperative Cognitive DysfunctionPostoperative Delirium

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