An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Summary

This trial investigates whether hyperpolarized magnetic resonance imaging (hpMRI) can predict treatment response in patients with thyroid cancer and other malignancies of the head and neck undergoing radiation therapy and/or receiving systemic therapy before surgery. An hpMRI is like a standard MRI but involves the use of an imaging contrast agent called hyperpolarized 13-C-pyruvate. Diagnostic procedures, such as hpMRI, may predict a patient's response to treatment and may help plan the best treatment.

Eligibility

Inclusion Criteria:

* Be willing and able to provide informed consent
* Be informed of the investigational nature of this study
* Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment

Exclusion Criteria:

* Have a history of severe claustrophobia
* Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI)
* Have a history of cardiac arrhythmia
* Have an allergy to Gadavist intravenous contrast
* Estimated glomerular filtration rate (eGFR) \< 30
* If female, be pregnant or breast feeding at time of consent

Conditions2

Locations1 site

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