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Prospective 4D CTA of BAV Competence
RECRUITINGSponsored by University of Pennsylvania
Actively Recruiting
SponsorUniversity of Pennsylvania
Started2020-12-01
Est. completion2027-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT04645862
Summary
The study involves annual 4D CTA imaging of the bicuspid aortic valve for a period of 5 years. CTA is often standard of care for BAV patients, but patients in this study will receive a higher radiation dose with a 4D imaging protocol. There may also be patients enrolled in the study who have a 4D CTA for research purposes when a routine CTA is not required for clinical care.
Eligibility
Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria: * At least 18 years of age * Documented bicuspid aortic valve identified via clinical imaging (e.g., CT, MRI, or echocardiogram) with minimal calcification at the time of enrollment * Participant must sign the informed consent form Exclusion Criteria: * Pregnancy (determined by point of care urine pregnancy test) * Renal failure (estimated Glomerular Filtration Rate (eGFR) \< 30), precluding them from receiving intravenous contrast) * Documentation of previous intravenous contrast allergy (unless they are having a CT with steroid preparation as part of routine clinical care) * Previous aortic valve replacement
Conditions2
BicuspidHeart Disease
Locations1 site
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.
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Actively Recruiting
SponsorUniversity of Pennsylvania
Started2020-12-01
Est. completion2027-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT04645862