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Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

RECRUITINGSponsored by Kliniken Beelitz GmbH
Actively Recruiting
SponsorKliniken Beelitz GmbH
Started2017-09-01
Est. completion2027-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or
* diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or
* diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015)
* Hoehn and Yahr Stage within the range of I-V or
* diagnosis of motor neurone disease or
* diagnosis of a neurodegenerative disease other than specified above

AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019).

Exclusion Criteria:

\- Patients who do not sign the consent form

Conditions6

Motor Neuron DiseaseMultiple System AtrophyNeurodegenerative DiseasesParkinson DiseaseParkinson's DiseaseProgressive Supranuclear Palsy

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