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Neural Correlates of Psychiatric Disorders

RECRUITINGSponsored by Vanderbilt University Medical Center
Actively Recruiting
SponsorVanderbilt University Medical Center
Started2021-03-31
Est. completion2026-02
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Undergoing SEEG monitoring at Vanderbilt University Medical Center
* At least 18 years of age
* English speaking

Exclusion Criteria:

* Age \<18
* Not able to complete questionnaires (e.g., unable to comprehend instructions or follow directions)

Conditions4

AnxietyDepressionMemory DisordersPsychiatric Disorder

Locations1 site

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
Sarah Bick, MD

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