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Investigating Inhibitory Control Networks in Parkinson's Disease

RECRUITINGN/ASponsored by University of Alabama at Birmingham
Actively Recruiting
PhaseN/A
SponsorUniversity of Alabama at Birmingham
Started2021-04-01
Est. completion2027-03-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT04735458

Summary

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Eligible for surgery based on multi-disciplinary consensus review
* Have a diagnosis of Parkinson's disease or Essential Tremor
* Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
* Willingness to participate in the paradigms described in the protocol

Exclusion Criteria:

* Inability to provide full and informed consent
* Age younger than 18
* Are not able to participate in study-related activities
* History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure

Conditions2

Parkinson DiseaseParkinson's Disease

Locations1 site

University of Alabama at Birmingham
Birmingham, Alabama, 35233
Nicole Bentley, MD205-975-0011jbentley@uabmc.edu

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