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Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

RECRUITINGSponsored by M.D. Anderson Cancer Center
Actively Recruiting
SponsorM.D. Anderson Cancer Center
Started2020-02-13
Est. completion2025-11-30
Eligibility
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT04743466

Summary

This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels may be associated with an increased risk of dementia. Learning about the association between testosterone levels and risk of dementia may help determine the long-term effects of androgen deprivation therapy and may help improve quality of life.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Have volunteered to participate in institutional or national biobanks, mainly the UK Biobank and the Kaiser Permanente Research Bank, and those that have previously participated in studies that resulted in de-identified clinical and genetic data being make available on public archives, mainly the database of Genotypes and Phenotypes (dbGaP)
* No special populations (adults unable to consent, individuals not yet adults, pregnant women, or prisoners)

Conditions7

AnxietyAnxiety DisorderCancerDepressionGenetic DisorderHematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm

Locations1 site

M D Anderson Cancer Center
Houston, Texas, 77030
Kevin Nead713-563-5155ktnead@mdanderson.org

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