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Intraoperative Tumor Margin Identification With ICG Dye Imaging

RECRUITINGPhase 2Sponsored by Massachusetts General Hospital
Actively Recruiting
PhasePhase 2
SponsorMassachusetts General Hospital
Started2022-05-25
Est. completion2025-12-01
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

In this research study we want to learn more about the use of indocyanine green (ICG) during bone or soft tissue mass resections. Indocyanine green (ICG) is a type of dye that is used in medical diagnostics. We want to determine if ICG-guided tumor resection is more effective in obtaining negative margins. Lastly, we want to assess traditional oncologic outcomes of local recurrence, time to metastatic disease, and overall and disease specific survival.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* All patients 18 years of age or older who present to Massachusetts General Hospital Department of Orthopaedic Surgery with a benign or malignant bone or soft tissue mass that is consented for surgery during the study period.

Exclusion Criteria:

* Pregnant or nursing patients
* Patients with previously known anaphylaxis to IV contrast or iodine (other allergies may be considered on a case-by-case basis)
* Patients in renal failure who are not cleared for ICG administration by their primary physician or oncologist

Conditions3

Benign NeoplasmCancerMalignant Neoplasm

Locations1 site

Massachusetts General Hospital
Boston, Massachusetts, 02114
Santiago A Lozano-Calderon, MD, PhD(617) 643-4947slozanocalderon@mgh.harvard.edu

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