|

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone with the NOGA System

RECRUITINGN/ASponsored by University Hospital, Toulouse
Actively Recruiting
PhaseN/A
SponsorUniversity Hospital, Toulouse
Started2022-02-23
Est. completion2025-12-31
Eligibility
Age18 Years – 85 Years
Healthy vol.Accepted

Summary

Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters. However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility. However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.

Eligibility

Age: 18 Years – 85 YearsHealthy volunteers accepted
Inclusion Criteria:

\- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation)

OR

* patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation)
* Affiliated with a social protection scheme
* Having signed an informed consent

Exclusion Criteria:

* Contraindication or non-indication for ventricular tachycardia ablation
* Women who are pregnant or of childbearing age and without contraception, breastfeeding women
* Patients without ischemic heart disease
* Patients under guardianship, curatorship or legal protection.

Conditions2

Heart DiseaseMyocardial Infarction

Browse More Trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.