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Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease

RECRUITINGSponsored by Guangzhou University of Traditional Chinese Medicine
Actively Recruiting
SponsorGuangzhou University of Traditional Chinese Medicine
Started2021-06-01
Est. completion2026-06-30
Eligibility
Age55 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04804618

Summary

This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use liquid chromatography/mass spectrometry (LC-MS/MS) technology to explore early warning indicators of protein in patients with mild cognitive impairment and Alzheimer's disease

Eligibility

Age: 55 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Older than 55-year-old，male or female.
2. patients meet the diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease(AD) or whose family members were diagnoed with AD
3. Complete self-rating scale for memory impairment (AD-8 scale)
4. Those who agree to participate in clinical research and sign informed consent.

Exclusion Criteria:

1. Patients with acute cardiovascular and cerebrovascular diseases, acute infections (pneumonia, urinary tract infection, oral infection, digestive tract infection), severe renal dysfunction, and uremia;
2. Pregnant or lactating women;

Conditions3

Alzheimer Disease, Early OnsetAlzheimer's DiseaseProtein; Disease

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