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Detecting HPV DNA in Anal and Cervical Cancers

RECRUITINGSponsored by University of Chicago
Actively Recruiting
SponsorUniversity of Chicago
Started2020-10-06
Est. completion2027-11-15
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations2 sites
View on ClinicalTrials.gov →

NCT04857528

Summary

This is a research study for individuals who have cancer associated with human papillomavirus (HPV) and are being treated with radiation as part of standard care for their cancer. Doctors leading this study will use blood tests to find out if they can detect the HPV virus in the blood of study participants before, during, and after radiation treatment. They will also collect blood and archival tumor tissue (from a previous biopsy) to perform other tests in the future that could provide more information about HPV-associated cancers and how they respond to treatment. Participation in this study will last approximately 2 years.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Stage I-III anal cancer or stage I-IVA cervical cancer that is p16+ based on immunohistochemistry.
* Age ≥ 18 years
* Planned to undergo radiation therapy as definitive treatment, with or without concurrent systemic therapy

Exclusion Criteria:

* Anal carcinoma not associated with HPV-16, 18, 31, 33, or 35 will be removed from the
* Planned to undergo radiation therapy as an adjuvant or post-operative therapy

Conditions7

Anal CancerCancerCervical CancerHPV-Related Anal Squamous Cell CarcinomaHPV-Related CarcinomaHPV-Related Cervical CarcinomaUterine Cervical Cancer

Locations2 sites

University of Illinois at Chicago
Chicago, Illinois, 60612
Meredith Russellmrussel3@uic.edu
University of Chicago
Chicago, Illinois, 60637
Clinical Trials Intake855-702-8222cancerclinicaltrials@bsd.uchicago.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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