|

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

RECRUITINGSponsored by University of Colorado, Denver
Actively Recruiting
SponsorUniversity of Colorado, Denver
Started2021-06-02
Est. completion2026-07-09
Eligibility
Age5 Years – 13 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT04993859

Summary

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

Eligibility

Age: 5 Years – 13 YearsHealthy volunteers accepted
Inclusion Criteria:

* Children aged 5-13 years old
* A history of cancer
* Treatment with a chemotherapy regimen including VCR and/or DOX
* Completion of chemotherapy at least one year prior to study enrollment and survey completion.

Exclusion Criteria:

* Patients with a:
* Primary pelvic tumor
* Pelvic irradiation
* Pre-existing bladder/bowel dysfunction
* Spinal defects
* Neurologic disorder
* Neuro-oncologic tumor or brain metastasis
* Cyclophosphamide or ifosfamide therapy

Conditions3

Bladder DysfunctionCancerSurvivors of Childhood Cancer

Locations1 site

Children's Hospital Colorado
Aurora, Colorado, 80045
Gemma Beltran(720) 777-4418gemma.beltran@childrenscolorado.org

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.