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Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

RECRUITINGSponsored by M.D. Anderson Cancer Center
Actively Recruiting
SponsorM.D. Anderson Cancer Center
Started2020-01-09
Est. completion2026-10-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05011045

Summary

This study assesses neurocognitive outcomes after receiving radiation therapy to the brain (whole brain radiation therapy) in patients with blood cancers (hematologic malignancies). This may help researchers learn more about the effects of whole brain radiation therapy on memory and thinking in patients with blood cancer.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age 18 years or older
* Treatment with radiation therapy to the brain for a hematologic malignancy (ex. primary central nervous system lymphoma \[PCNSL\], secondary central nervous system lymphoma \[SCNSL\], leukemia, myeloma)
* Proficient and capable of completing tests in English
* Patients with claustrophobia are eligible if the claustrophobia is managed with medication
* Patients with cognitively-impairment are eligible if the impairment is managed with medication
* Patients who are pregnant

Conditions7

CancerCentral Nervous System LymphomaHematopoietic and Lymphoid Cell NeoplasmLeukemiaLymphomaPlasma Cell MyelomaSecondary Central Nervous System Lymphoma

Locations1 site

M D Anderson Cancer Center
Houston, Texas, 77030
Dustin M. Silk713-563-3090dmsilk@mdanderson.org

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