Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy

Summary

This study does not involve a therapeutic intervention as standard radiation therapy treatment will be prescribed. This study involves one additional 4DCT scan (i.e. the Real-Time Gated 4DCT scan) acquired immediately before or following the conventional 4DCT scan. This will take place on the day of the patient's treatment simulation, as per the current standard of care. The scanning sequence (i.e. conventional first versus gated first) will be randomised. The Real-Time Gated 4DCT is anticipated to take longer than the conventional 4DCT scan, due to its gated (beam-pause) nature. However, upper limits for timing will be implemented in the software, and the scan aborted for highly erratic breathing traces that would not benefit from a Real-Time Gated 4DCT scan.

Eligibility

Inclusion Criteria:

* 18 years or older
* Have the ability to give informed consent
* A diagnosis of lung cancer with an indication for radiation therapy
* Radiation therapy treatment involving the acquisition of a 4DCT scan for treatment planning

Exclusion Criteria:

* Pregnant women
* Patients \<18 years
* Patients who in the opinion of the treating physician could not tolerate the extra time on the CT couch for an extra scan

Conditions2

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