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Early Ageing During Therapy in AYA Cancer Patients

RECRUITINGSponsored by University Medical Center Groningen
Actively Recruiting
SponsorUniversity Medical Center Groningen
Started2022-02-10
Est. completion2025-07
Eligibility
Age18 Years – 39 Years
Healthy vol.Accepted

Summary

Longitudinal cohort study; measurements before start of systemic therapy and one year later.

Eligibility

Age: 18 Years – 39 YearsHealthy volunteers accepted
Inclusion Criteria:

* Aged 18-39 years at cancer diagnosis
* Having a histologically and/or cytologically confirmed cancer diagnosis, including leukemia, (non-)Hodgkin lymphoma, testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, and cervical cancer.
* Scheduled to start systemic therapy with curative intent. Allowed treatments (concurrent or sequential) are: surgery, radiotherapy, chemotherapy, antibodies.

Exclusion Criteria:

* patients who are not able to understand the patient information letter and informed consent form
* patients who will be treated with immune checkpoint inhibitors or targeted therapy with inhibitors of angiogenesis
* patients who have been treated with systemic therapy or radiotherapy for a previous malignancy (exceptions: in situ carcinoma of the cervix or uterus and adequately treated basal and squamous cell carcinoma of the skin).

Conditions8

Breast CancerCancerCervical CancerEwing SarcomaHodgkin LymphomaLeukemiaOsteosarcomaTesticular Cancer

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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