Telephone-Based Support Programs for People With Epilepsy

Summary

This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will also examine mediators and moderators of treatment effects.

Eligibility

Inclusion Criteria:

* adult (≥18 years of age);
* diagnosed with epilepsy for at least one year;
* fluent in English or Spanish;
* elevated depressive symptoms (PHQ-9 score ≥10);
* willing to participate in audiotaped group telephone sessions

Exclusion Criteria:

* severe depressive symptoms (PHQ-9 ≥20);
* active suicidal ideation (PHQ-9 item #9 ≥1 or otherwise reported during screening);
* active psychotic disorder (psychiatric diagnosis or antipsychotic medications in the EHR);
* significant cognitive impairment (indicated in EHR or evident during screening)

Conditions2

Locations1 site

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