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Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation

RECRUITINGN/ASponsored by Ottawa Heart Institute Research Corporation
Actively Recruiting
PhaseN/A
SponsorOttawa Heart Institute Research Corporation
Started2022-02-08
Est. completion2026-04-01
Eligibility
Age40 Years+
Healthy vol.Accepted

Summary

The main purpose of this pilot project is to measure the feasibility of conducting a randomized crossover study examining short-term changes in atrial fibrillation (AF) symptoms in symptomatic females and males with paroxysmal or persistent AF when they engage in a standard week of exercise (i.e. moderate-intensity continuous training \[MICT\] or high-intensity interval training \[HIIT\]) compared to a control week (i.e. no moderate to vigorous exercise over 7 days).

Eligibility

Age: 40 Years+Healthy volunteers accepted
Inclusion Criteria:

* Paroxysmal and Persistent AF
* Rate controlled (resting ventricular rate \<110 bpm)
* Able to do a symptom limited exercise test
* At least 40 years of age
* Self-reports being symptomatic in the past 4 weeks
* If female, self-reports being post-menopausal
* Able to read and understand English or French
* Agrees to sign informed consent

Exclusion Criteria:

* Currently participating in routine exercise training
* Unstable angina or uncontrolled diabetes mellitus; or established diagnosis of severe mitral or aortic stenosis, or hypertrophic obstructive cardiomyopathy with significant obstruction
* Unable to access the Internet or a phone (iPhone and iPad require iOS version 10.0 and up, Android requires version 6.0 and up) during the study period
* Has an automated external defibrillator, an implantable cardioverter defibrillator or other types of pacemaker
* Unwilling or unable to complete the three conditions
* Unable to provide written, informed consent

Conditions4

Atrial FibrillationHeart DiseaseParoxysmal Atrial FibrillationPersistent Atrial Fibrillation

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