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Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases

RECRUITINGSponsored by Mayo Clinic
Actively Recruiting
SponsorMayo Clinic
Started2021-11-01
Est. completion2026-10
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05122962

Summary

This study is being done to determine the mechanism(s) contributing to the onset of symptoms (i.e. shortness of breath and/or palpitations) as well as changes in heart structure in patients with congenital heart disease (CHD)

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Moderate (or greater) PR based on quantitative Doppler echocardiography.
* Repaired TOF
* Congenital Heart Disease diagnosis including but not limited to Ebstein's anomaly, coarctation of the aorta (COA), Fontan palliation, transposition of the great arteries, congenitally corrected transposition of the great arteries.

Exclusion Criteria:

* Pregnant Women
* Unable to undergo CMRI

Conditions3

Congenital Heart DiseaseHeart DiseaseTetralogy of Fallot

Locations1 site

Mayo Clinic in Rochester
Rochester, Minnesota, 55905
Halley Davison507-422-6246RSTACHDRESPRG@mayo.edu

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