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Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease

RECRUITINGN/ASponsored by University of Melbourne
Actively Recruiting
PhaseN/A
SponsorUniversity of Melbourne
Started2021-12-15
Est. completion2026-02-28
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age \>18 years
* Clinical indication to commence long term NIV
* Confirmed clinical diagnosis of underlying condition

Exclusion Criteria:

* Medically unstable
* Hypoventilation attributable to medications with sedative/respiratory depressant side- effects
* Use of NIV for more than 1 month in the previous 3 months
* Inability to provide informed consent
* Previous intolerance of NIV

Conditions2

Motor Neuron Disease, Amyotrophic Lateral SclerosisMultiple Sclerosis

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