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Clinical Trial of Approaches to Prostate Cancer Surgery

RECRUITINGN/ASponsored by Weill Medical College of Cornell University
Actively Recruiting
PhaseN/A
SponsorWeill Medical College of Cornell University
Started2023-05-15
Est. completion2028-07
Eligibility
Age40 Years – 80 Years
SexMALE
Healthy vol.Accepted
Locations9 sites

Summary

This is a prospective, randomized controlled trial to compare cancer control and health-related quality of life following pelvic fascia-sparing radical prostatectomy versus standard radical prostatectomy. The investigators hypothesize that pelvic fascia-sparing radical prostatectomy will have similar cancer control (primary outcome) and sexual function outcomes; and significantly better urinary function, penile shortening/deformity and inguinal hernia risks as compared to radical prostatectomy.

Eligibility

Age: 40 Years – 80 YearsSex: MALEHealthy volunteers accepted
Inclusion Criteria:

* Male sex
* Age ≥40 years or ≤80 years
* Scheduled for radical prostatectomy for clinically localized prostate cancer
* Able to read and speak English or Spanish
* Willingness to sign informed consent and adhere to the study protocol

Exclusion Criteria:

* Prior major pelvic surgery or radiotherapy
* Suspicion of N1 disease (i.e., any lymph node greater than 1cm in maximal diameter)

Conditions2

CancerProstate Cancer

Locations9 sites

Beckman Research Institute of City of Hope
Duarte, California, 91010
Radhika Nagalla, PharmD847-502-0334rnagalla@coh.org
Georgetown University
Washington D.C., District of Columbia, 20007
Keith Kowalczyk, MDKeith.Kowalczyk@medstar.net
Northwestern University
Mary Kate Keeter, MPH312-694-6082mary.fitzgerald@northwestern.edu
Johns Hopkins University
Rana Harb, MS410-502-5500rharb1@jhmi.edu
Beth Israel Deaconess Medical Center (BIDMC)
Gabriela Nieto Blanco, MS617-632-1047gnietobl@bidmc.harvard.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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