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Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches

RECRUITINGN/ASponsored by Veterans Medical Research Foundation
Actively Recruiting
PhaseN/A
SponsorVeterans Medical Research Foundation
Started2022-01-01
Est. completion2025-08-31
Eligibility
Age18 Years – 65 Years
Healthy vol.Accepted
Locations1 site

Summary

This study will assess the combined effectiveness of repetitive transcranial magnetic stimulation (rTMS) and telehealth based therapy in helping manage mild traumatic brain injury (mTBI) related headaches. The investigators hypothesize that active rTMS combined with telehealth therapy will provide marked reduction in mTBI related headaches and symptoms in comparison to their placebo counterparts.

Eligibility

Age: 18 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

1. Mild Traumatic Brain Injury (mTBI)
2. Chronic headaches \> 3 months after injury
3. Aged 18-65
4. No prior TMS treatment
5. Persistent Headaches with an intensity \> 30 / 100
6. No history of daily headache prior to mTBI

Exclusion Criteria:

1. Pregnant
2. Pacemaker or any metal in body that would prevent MRI
3. History of dementia or major psychiatric disease, such as bipolar disorder or schizophrenia
4. Presence of any other chronic neuropathic pain states
5. History of seizure
6. Pending litigation
7. Can't understand English
8. History of chronic headache like migraine prior to mTBI
9. Evidence in chart of exacerbation of depressive/anxiety symptoms, active substance dependence, suicidal intent or attempt within previous month

Conditions3

DepressionHeadacheTBI (Traumatic Brain Injury)

Locations1 site

VA San Diego Healthcare System
San Diego, California, 92161
Caleb Lopez, BS858-552-8585caleb.lopez@va.gov

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