Molecular Epidemiology of Biliary Tree Cancers

Summary

This study is to learn if certain risk factors (environmental, viral, behavioral, medical, and dietary), tumor markers, and genetic changes can predict the development and outcome of biliary tree cancers. Establishing biomarkers models from patients may help doctors to further understand how biliary tree cancer is affected by different treatments, and why some people's cancer responds differently than others.

Eligibility

Inclusion Criteria:

* Pathologically or radiologically confirmed diagnosis of CGC or GBC
* With or without prior radiation or chemotherapy
* All United States of America (USA) and non USA residents
* No age, gender, or racial restriction
* Healthy control with no current or history of cancer
* Healthy controls are USA and non USA residents
* Healthy controls are matched to the cases in age (5 years), gender, and race
* Healthy controls are friends and spouses of patients with other than gastro-intestinal (GI) cancers
* Chronic Liver Disease (CLD) controls with no current or history of cancer
* CLD controls are USA and non USA residents
* CLD controls are frequency matched to CGC cases by age (5 years), gender, and race
* CLD controls are patients are diagnosed with or without liver biopsy (core or fine needle aspiration)
* CLD controls must not have evidence liver cancer diagnosis by computed tomography (CT) or magnetic resonance imaging (MRI)

Exclusion Criteria:

* None

Conditions3

Locations1 site

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