Exercise and the Menstrual Cycle in Type 1 Diabetes

Summary

Female participants with type 1 diabetes using oral contraceptives will be asked to wear a continuous glucose monitor for at least three days on two separate occasions (once during the last week of active pills and once during the no pill/placebo pill phase of the menstrual cycle). An exercise session (45 minutes of aerobic exercise at 60% VO2peak on a cycle ergometer) will take place at 5 pm on the second day of glucose monitoring.

Eligibility

Inclusion Criteria:

* type 1 diabetes diagnosed for at least 1 year
* regular menses
* using monophasic oral contraceptives
* residing in Edmonton, Alberta and able to visit the lab at the University of Alberta

Exclusion Criteria:

* HbA1c \> 9.9%
* frequent and unpredictable hypoglycemia
* change in insulin management strategy within two months of the study
* use of an automated insulin delivery system
* blood pressure \> 140/95
* history of cardiovascular disease
* severe peripheral neuropathy
* active proliferative retinopathy
* use of medications (other than insulin) that would affect blood glucose levels
* any musculoskeletal condition that would contraindicate exercise (e.g. sprain, strain, joint injury, etc.)

Conditions2

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