Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Summary

Participants will be asked to wear a continuous glucose monitor for at least three days on three separate occasions. One testing session will be a no-exercise resting control session (90 minutes). One will be a moderate aerobic exercise session (30 minutes of exercise, 60 minutes of recovery), and the third will be a moderate weight-lifting session (\~30 minutes of exercise, 60 minutes of recovery).The investigators will measure changes in blood glucose during exercise by drawing blood during and after exercise. Post-exercise glucose trends will be examined using continuous glucose monitoring.

Eligibility

Inclusion Criteria:

* type 1 diabetes, diagnosed for at least one year
* post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy
* able to perform aerobic and resistance exercise
* able to visit the lab in Edmonton, Alberta (University of Alberta)

Exclusion Criteria:

* HbA1c \> 9.9 %
* frequent and unpredictable hypoglycemia
* change in insulin management strategy within the last 2 months
* blood pressure \> 140 / 95
* severe peripheral neuropathy
* history of cardiovascular disease
* musculoskeletal injuries interfering with exercise performance
* use of medications (other than insulin) that affect glucose metabolism
* BMI \> 30 kg/m2
* smoking
* moderate to high alcohol intake (\> 2 drinks/day)

Conditions3

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