|

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

RECRUITINGN/ASponsored by Massachusetts General Hospital
Actively Recruiting
PhaseN/A
SponsorMassachusetts General Hospital
Started2025-07-21
Est. completion2026-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations2 sites

Summary

This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Adult patients ≥ 18 years old with diagnosis of cirrhosis based on histology, radiology, and/or elastography presenting to the emergency department or inpatient general medicine service
2. Patients must have one of the following:

   1. Ascites (requiring diuretics or serial large volume paracenteses)
   2. Hepatic hydrothorax (requiring diuretics)
   3. Hepatic encephalopathy (requiring medications)

Exclusion Criteria: All existing MGB home hospital criteria apply, with the following taking precedent for this specific condition

1. History of solid organ transplantation
2. On hemodialysis
3. MELD score \> 20
4. Score \<10 on Simplified Animal Naming Test (S-ANT1)
5. Current admission for hemodynamically significant GI bleeding or alcohol withdrawal
6. Require routine administration of controlled substances
7. Those deemed ineligible based on the MGH Home Hospital, inpatient medicine or hepatology clinician evaluation

Conditions5

CirrhosisEnd Stage Liver DiseaseLiver CirrhosisLiver DiseaseLiver Disease Chronic

Locations2 sites

Massachusetts General Hospital
Boston, Massachusetts, 02114
Will Munroe, BA617-726-0161wlmunroe@mgh.harvard.edu
Massachusetts General Hospital
Boston, Massachusetts, 02114

Browse More Trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.