Effect of Electroacupuncture on Obesity

Summary

The investigators describe a protocol for a randomized controlled trial to find out the effect and safety of electroacupuncture on losing weight in obese patients with prediabetes.

Eligibility

Inclusion Criteria:

1. Male or female participants aged 18-65;
2. Participant whose BMI is ≥24.0 kg/m2;
3. Participants whose HbA1c measurement of 5.7-6.4% both inclusive, or fasting plasma glucose measurement ≥ 6.1 mmol/liter and \<7.0 mmol/liter, or 2-hour plasma glucose measurement post-challenge (oral glucose tolerance test) ≥7.8 mmol/liter and \<11.1 mmol/liter;
4. Participants with stable weight within 3 months before the start of the trial, fluctuated within 4 kg;
5. Participants who voluntarily agree with the investigation and sign a written informed consent form for the clinical trial.

Exclusion Criteria:

1. Patients with secondary obesity caused by drugs or neuro-endocrine-metabolic disorders (such as hypothalamic disease and hypopituitarism);
2. Patients who have been diagnosed with type I or type II diabetes;
3. Patients who are taking medication which cause clinically significant weight gain or loss;
4. Patients whose Hamilton 17-item Depression Scale (HAMD-17) score \>18 or have a history of other severe psychiatric disorders;
5. Patients with severe ulcer, abscess and skin infection at the local acupuncture area;
6. Patients with severe diseases of multiple organs, such as heart, brain, lungs, liver, kidneys, hematopoietic system or other serious diseases;
7. Participants who have joined in other clinical trials or studies within the past 1 month;
8. Pregnant or lactating women.

Conditions3

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