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Prehabilitation for Patients Awaiting Liver Transplantation

RECRUITINGN/ASponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre
Actively Recruiting
PhaseN/A
SponsorMcGill University Health Centre/Research Institute of the McGill University Health Centre
Started2022-02-23
Est. completion2025-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05237583

Summary

This study will assess the feasibility, safety and effectiveness of a structured prehabilitation program combining exercise training, nutritional optimization and psychological support for patients with cirrhosis awaiting liver transplantation.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age above 18 years
* Diagnosis of cirrhosis, based on a combination of clinical, laboratory, imaging, or histology
* Active on the liver transplant waiting list of the MUHC

Exclusion Criteria:

* Biological Model for End Stage Liver Disease \>20
* Hepatic decompensation within the last month
* High risk varices not on primary or secondary prevention
* Recurrent large volume paracentesis
* Persistent hepatic encephalopathy
* Platelets \<20,000/µL, or hemoglobin \<80g/L
* Altered hemodynamics
* Significant heart disease
* Awaiting combined organ transplantation
* Awaiting repeat liver transplantation
* Condition limiting mobilization and/or exercise, or recurrent falls

Conditions4

Cirrhosis, LiverFrailtyLiver DiseaseLiver Transplantation

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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