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Gut Permeability and Bariatric-metabolic Surgery

RECRUITINGSponsored by Medical University of Vienna
Actively Recruiting
SponsorMedical University of Vienna
Started2021-05-01
Est. completion2025-12
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05257200

Summary

Increased intestinal permeability and dysbiosis have been causally associated with NAFLD and NASH progression. However, to date, there are no systematic studies, on the effect of bariatric-metabolic surgery on intestinal permeability and dysbiosis in the context of NAFLD development.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients with morbid obesity undergoing bariatric metabolic surgery according to the IFSO criteria,
* Willingness to attend all follow-up visits
* Written consent

Exclusion Criteria:

* other liver disease than NAFLD
* presence of IBD, acute pancreatitis, amyotrophic lateral sclerosis, pregnancy

Conditions4

Bariatric Surgery CandidateIntestinal PermeabilityLiver DiseaseNASH - Nonalcoholic Steatohepatitis

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