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Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

RECRUITINGSponsored by University of Turku
Actively Recruiting
SponsorUniversity of Turku
Started2023-01-11
Est. completion2028-12
Eligibility
Age18 Years – 74 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05278520

Summary

The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.

Eligibility

Age: 18 Years – 74 YearsHealthy volunteers accepted
Inclusion Criteria for the main (OA) study:

Cases: Adult patients with osteoarthritis in the hip joint and who are going through an elective total hip arthroplasty.

Controls: Non-arthritis adult patients who are going through a trauma-based emergency total hip arthroplasty.

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Inclusion Criteria for the Rheumatoid sub-study:

Adult patients with rheumatoid arthritis in the hip joint and who are going through an elective total hip arthroplasty.

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Exclusion Criteria:

* The body mass index must be below 35
* Age \< 18 or \> 74
* The OA patients may not have diabetes, rheumatoid arthritis (RA), or metabolic syndrome.

For the Rheumatoid sub-study, the exclusion criteria are the same as above except for the RA.

Conditions3

ArthritisOsteoarthritis, HipRheumatoid Arthritis

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