Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway

Summary

The primary objective of this study is to assess the feasibility and impact of implementing the ESC 0-1 hour high sensitive troponin pathway in clinical practice and with specific reference to the 0-3 hour pathway currently in use. The principal outcome measure will be the safety of the 0-1 hour protocol (which is less established and has limited data on safety when implemented in clinical practice)

Eligibility

Inclusion Criteria:

* Chest pain with moderate or high suspicion chest pain (see chest pain evaluation chart at end) or any patient the clinician deems suspicious for myocardial ischaemia thus requesting a troponin sample (between daytime hours 0800hrs to 1800hrs)
* Presentation \<12 hours since onset of chest pain (or unknown duration)
* Age \>18 years of age

Exclusion Criteria:

* ST elevation myocardial infarction (STEMI) infarct on the presenting electrocardiogram (ECG)
* Symptoms considered definitely non-cardiac
* Trauma
* Pregnancy
* Comorbid conditions requiring hospital admission
* Coronary artery bypass graft surgery (CABG) \<1 month
* coexistent clinical conditions likely to preclude follow-up.

Conditions5

Browse More Trials