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MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy

RECRUITINGN/ASponsored by Centre Hospitalier Universitaire de Besancon
Actively Recruiting
PhaseN/A
SponsorCentre Hospitalier Universitaire de Besancon
Started2022-04-15
Est. completion2025-07
Eligibility
Age18 Years – 85 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05333367

Summary

The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.

Eligibility

Age: 18 Years – 85 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adult patients
* Treated with ECP for at least 1 month, for control of GVHD in hematopoietic cell allograft (acute or chronic GVHD), treatment and control of cellular or humoral rejection in solid organ transplantation (heart, lung, kidney) or in the treatment of cutaneous T-cell lymphoma

Exclusion Criteria:

* Subjects with limited legal capacity.
* Subjects judged by the investigator to be unlikely to comply with study procedures
* Subjects with no social security coverage.
* Pregnant women.
* Subjects still in the exclusion period of another study, or according to the national registry of clinical trial participants.

Conditions4

CancerCutaneous T Cell LymphomaGraft RejectionGraft vs Host Disease

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