Systematic Light Exposure in Pediatric Brain Tumor Survivors

Summary

Children and adolescents treated for a brain tumor often experience fatigue and cognitive symptoms, such as slowed information processing and inattention. These symptoms may cause difficulty carrying out daily activities at home and at school. There are few well-researched, non-pharmacological interventions aimed at improving symptoms of fatigue and by extension cognitive symptoms. Systematic bright light exposure has been shown to improve symptoms of fatigue in adult survivors of cancer and children treated for some forms of cancer. This is a pilot/feasibility study and the first known study in children treated for a brain tumor. Findings from this study will be used to help plan a larger study to examine the effectiveness of this intervention and mechanisms of action. PRIMARY OBJECTIVE: 1. To evaluate feasibility and adherence in a study of systematic bright light exposure used to improve fatigue and cognitive efficiency in survivors of pediatric brain tumor, including rates of enrollment, adherence, and acceptability. SECONDARY OBJECTIVES: 2. To estimate the effect size of change in fatigue associated with bright light exposure. 3. To estimate the effect size of change in cognitive efficiency associated with bright light exposure.

Eligibility

Inclusion Criteria:

* Diagnosed and treated for a brain tumor at Texas Children's Hospital
* Treated with either surgery only or surgery and proton beam radiation therapy
* Treated for tumors other than high-grade gliomas, brain stem gliomas, or atypical teratoid rhabdoid tumors given associated reduced survival rates
* Currently or previously enrolled in longitudinal studies of neurocognitive outcomes in survivors of pediatric brain tumor (Lisa Kahalley, PI; H-29026, H-35681, H-40804, H-40961, H-49380, H-26785, H-41705
* Ages 10-18 years
* At least 1 year post-diagnosis
* Endorsed mild to moderate symptoms of fatigue on the PROMIS
* Approval from Long-Term Survivorship provider
* Adequate vision for computerized tasks
* English-speaking
* Intelligence Quotient (IQ) above 70

Exclusion Criteria:

* Diagnosis and/or treatment for secondary malignancy in the past 12 months
* Current or previous (within 12 months) suicidal ideation or severe depression requiring immediate intervention
* Presence of photophobia or other eye diseases, seizures, and/or migraines
* Use of photosensitizing medications
* Current or previous use of light therapy

Conditions2

Locations1 site

Browse More Trials