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Predictors of Failed Thrombolysis in Acute Myocardial Infarction

RECRUITINGSponsored by Oslo University Hospital
Actively Recruiting
SponsorOslo University Hospital
Started2022-04-25
Est. completion2025-04-25
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The purpose of this observational study is to assess why thrombolytic treatment with tissue-plasminogen activator (t-PA) fails in patients with acute ST-segment elevation myocardial infarction (STEMI). The study will include 200 STEMI patients at the time of arrival at Oslo University Hospital Ullevål after receiving prehospital thrombolysis. A blood sample will be taken immediately for the study of factors related to coagulation, fibrinolysis and inflammation. Levels of the biomarkers will be compared between patients with successful and failed thrombolysis.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

STEMI patients \> 18 years given prehospital thrombolysis.

Exclusion Criteria:

None.

Conditions2

Heart DiseaseSTEMI - ST Elevation Myocardial Infarction

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