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PV Loop & Coarctation Study

RECRUITINGSponsored by University of Minnesota
Actively Recruiting
SponsorUniversity of Minnesota
Started2019-06-04
Est. completion2026-12-31
Eligibility
Age6 Years+
Healthy vol.Accepted
Locations7 sites
View on ClinicalTrials.gov →

NCT05362721

Summary

Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.

Eligibility

Age: 6 Years+Healthy volunteers accepted
Inclusion Criteria:

* Children 6 years of age and older and adults of all races and both sexes referred for elective cardiac catheterization and stent therapy for coarctation
* Those who provide informed consent for study participant.

Exclusion Criteria:

* Children who undergo other interventions in addition to the coarctation
* Children with single ventricle physiology.
* Renal impairment
* Participant unwilling to sign a consent form.

Conditions2

Coarctation of AortaHeart Disease

Locations7 sites

Children's Hospital of Los Angeles
Los Angeles, California, 90027
Neil Patelneipatel@chla.usc.edu
Children's Hospital of Boston
Boston, Massachusetts, 02115
Nikhil Thatte, MDnikhil.thatte@cardio.chboston.org
Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503
Oliver Aregullin, MD616-267-9150oliver.aregullin@helendevoschidlrens.org
University of Minnesota
Minneapolis, Minnesota, 55455
Brittany Faanes612-625-5929grego318@umn.edu
Children's Mercy Hospital
Kansas City, Missouri, 64108
Toby Rockefeller, MDtarockefeller@cmh.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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