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The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

RECRUITINGN/ASponsored by Stanford University
Actively Recruiting
PhaseN/A
SponsorStanford University
Started2022-10-04
Est. completion2026-07
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05379673

Summary

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status I-III
* Body mass index (BMI) less than 40 kg/m2
* Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.

Exclusion Criteria:

* Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
* Chronic pain condition that is being treated with opioids
* Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

Conditions3

DepressionPostoperative Respiratory FailureVentilatory Depression

Locations1 site

Stanford University School of Medicine
Stanford, California, 94305
Anthony Doufas, MD, PhD(650) 498-7699agdoufas@stanford.edu

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