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SOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome

RECRUITINGSponsored by Guy's and St Thomas' NHS Foundation Trust
Actively Recruiting
SponsorGuy's and St Thomas' NHS Foundation Trust
Started2022-06-01
Est. completion2025-06-30
Eligibility
Age18 Years+

Summary

In this study, we aim to assess whether Patient Derived Organoids can be used to predict treatment sensitivity in HNSCC patients.

Eligibility

Age: 18 Years+
Inclusion Criteria:

* Patients with head and neck squamous cell carcinoma (including oral cavity, oropharynx, paranasal sinuses, hypopharynx or larynx) undergoing curative treatment (primary surgery or radiotherapy) or presenting with recurrent or metastatic cancers
* Age \> 18 years old

Exclusion Criteria:

* Patients unable to give informed consent e.g. mental disability or vulnerable adults

Conditions3

CancerHead and Neck CancerHead and Neck Squamous Cell Carcinoma

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