Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep

Summary

The purpose of our study is to understand the impact of different meal timing alterations on blood sugars, metabolism, microbiome and sleep physiology in people with prediabetes and diabetes; and to study the temperature/heart rate response to different meals in different people.

Eligibility

Inclusion Criteria:

* Be 18 years of age or older;
* Not be pregnant, if female;
* Be generally healthy (with no apparent symptoms at the time of enrollment)
* Patients with prediabetes or diet- controlled or type 2 diabetes or controlled with metformin, will also be allowed to participate.
* Be willing to provide written informed consent for all study procedures.

Exclusion Criteria:

* major organ disease
* pregnant/lactating
* diabetes medications except for metformin
* malabsorptive disorders like celiac sprue
* heavy alcohol use
* use of weight loss medications or specific diets
* weight change \>2 Kg in the last month
* history of bariatric surgery
* Any medical condition that physicians believe would interfere with study participation or evaluation of results
* Mental incapacity and/or cognitive impairment on the part of the patient that would preclude adequate understanding of, or cooperation with, the study protocol.

Conditions4

Locations1 site

Browse More Trials