3D-PCT Combined With CT-guided Radioactive I-125 Seed Implantation in the Treatment of Head and Neck Tumors

Summary

The purpose of this study is to verify the accuracy, short-term efficacy and side effects of 3D printing coplanar template combined with CT-guided I-125 seeds implantation in the treatment of malignant tumors of the head and neck.

Eligibility

Inclusion Criteria:

* the age is 18-80 years old;
* the pathological diagnosis is clear, patients with local recurrence / metastasis of head and neck tumor after operation or external radiotherapy;
* the tumor diameter ≤ 5cm, the number of lesions ≤ 3;
* there is a suitable puncture path, and the target dose of pre can reach the prescribed dose;
* KPS ≥ 70 points, the expected survival time is more than 3 months;
* patients have signed a consent form for I-125 seeds implantation therapy;
* patients have signed the consent form of knowing emotions to participate in this observational study;

Exclusion Criteria:

* coagulation dysfunction;
* tumor surface rupture, or tumor memory liquefied and necrotic in a large range, with poor expected particle distribution;
* severe underlying diseases, resulting in unsafe completion of I-125 seeds implantation therapy, including active infections requiring drug treatment;
* mental abnormalities affecting cognitive ability;
* poor compliance and inability to complete treatment;
* those who were considered unsuitable to participate in this clinical trial;

Conditions2

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