Glucose Monitoring After Acute Myocardial Infarct in People With Diabetes

Summary

Glucose monitoring after Acute Myocardial infarct in people with diabetes is a Dexcom funded study that is investigating whether the use of continuous glucose monitors (Dexcom ONE model) in people with type 2 diabetes facilitates time in glycaemic range in the 6 months after an acute myocardial infarction. As an exploratory outcome it will investigate whether time in glycaemic range is associated with changes in mortality and major adverse cardiac events in the 6 months after acute myocardial infarct.

Eligibility

Inclusion Criteria:

From the Hammersmith Hospital In-patient Cardiology Services:

* Adults aged \>18 years
* Known or newly diagnosed type 2 diabetes
* Taking one or more oral hypoglycaemic agent, GLP1 receptor analogue and/or insulin
* Admitted to Hammersmith Hospital cardiology inpatient services with ACS
* Raised blood troponin level on admission

From Imperial College Healthcare Trust Diabetes and Cardiology Clinics:

* Adults aged \>18 years
* Known type 2 diabetes
* Previous acute coronary syndrome within the last 10 years but \> 6 months ago
* Taking one or more oral hypoglycaemic agent and /or GLP1 receptor analogue, and/or insulin

Exclusion Criteria:

From the Hammersmith Hospital In-patient Cardiology Services:

* HbA1c \<48mmol/mol
* People who have previously had bariatric surgery
* People taking hydroxyurea
* People who undergo haemodialysis or peritoneal dialysis
* Unable to participate due to other factors, as assessed by the Chief Investigators
* Pregnancy as determined by clinical team
* Known to have a terminal condition or conditions that suggest a life expectancy less than 1 year

From Imperial College Healthcare Trust Diabetes and Cardiology Clinics:

* HbA1c \<48mmol/mol
* People who have previously had bariatric surgery
* People taking hydroxyurea
* People who undergo haemodialysis or peritoneal dialysis
* Unable to participate due to other factors, as assessed by the Chief Investigators
* Pregnancy as determined by clinical team
* Known to have a terminal condition or conditions that suggest a life expectancy less than 1 year
* Previous acute coronary syndrome more than 10 years ago or within the last 6 months

Withdrawal criteria

* The subject has a serious event related to the study
* Investigated initiated discontinuation of study due to participation or equipment concerns
* Withdrawal of consent

Conditions6

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