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Effect of StRess and ExeRcize on the Outcome After Chemo-Radiation

RECRUITINGSponsored by Maastricht Radiation Oncology
Actively Recruiting
SponsorMaastricht Radiation Oncology
Started2022-06-01
Est. completion2025-12
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05431348

Summary

Glioblastoma (GBM) is a highly malignant, incurable primary brain tumor. Due to the nature of this disease and the extent of the treatment (surgery followed by chemoradiation according to the Stupp trial) patients undergo considerable psychological distress. It is known that stress hormones are involved in a wide range of processes involved in cell survival, cell cycle and immune function, and can cause therapy resistance. In this study the effect of stress on outcome after chemoradiation in patients with GBM will be investigated.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients treated with Stupp or Elderly protocol: GBM WHO IV, astrocytoma WHO IV IDHmt, astrocytoma WHO II IDHwt (GBM-like).
* willing to wear the smart watch during the treatment protocol

Exclusion Criteria:

* younger than 18 years
* not in possession of a smart phone

Conditions2

CancerGlioblastoma (GBM)

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