Lung Nodule Detection Using Ultra-long FOV PET/CT

Summary

Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment. The introduction of long Field-Of-View PET/CT scanners could make a difference in this matter due to the substantial increase in sensitivity allowing optimal image quality. Whether this new technology could provide improved detection and follow-up of indeterminate lung nodules is what we aim to explore in this study.

Eligibility

Inclusion Criteria:

* able to give informed consent
* signed informed consent
* confirmed indeterminate lung nodule(s) of 6-15 mm in size on CT chest imaging
* routine 18F-FDG PET/CT performed
* scheduled for biopsy or resection of the lung nodules

Exclusion Criteria:

* claustrophobia
* pregnant or breastfeeding
* interval of at least 2 weeks between PET scan and last date of systemic anti-cancer therapy to reduce false-negative uptake in lesions
* radiation therapy of the target lung nodule(s)
* uncontrolled diabetes mellitus
* any medical condition potentially hampering conduction of the trial

Conditions2

Browse More Trials