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Lung Health of Early COPD: A Multi-center Cohort Study

RECRUITINGSponsored by Ting YANG
Actively Recruiting
SponsorTing YANG
Started2022-08-01
Est. completion2026-12-30
Eligibility
Age35 Years – 75 Years
Healthy vol.Accepted

Summary

This is a multi-center, prospective, cohort study in early COPD patients. This study aims to elucidate the lung function decline and its association with smoking and other risk factors. Other biomarkers and image markers from chest CT scan are also analyzed to investigate the lung function in early COPD patients.

Eligibility

Age: 35 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

1. Gender: male or female
2. Age: 35-75 years old
3. post-bronchodilator spirometry: FEV1/FVC \< 0.8 and FEV1%pred ≥80%

Exclusion Criteria:

1. Other diseases may affect lung function, like lung cancer, bronchiectasis, interstitial lung disease or chest surgery.
2. BMI \> 35 kg/m2
3. Dementia or other severe neurological disease
4. Pregnancy
5. Conditions that contraindicated lung function test

Conditions1

COPD

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