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Characterizing Sleep Among Long-term Survivors of Childhood Cancer

RECRUITINGSponsored by St. Jude Children's Research Hospital
Actively Recruiting
SponsorSt. Jude Children's Research Hospital
Started2023-04-17
Est. completion2026-07
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

The patients are being asked to take part in this clinical trial because they received cancer treatment as a child at St. Jude. The study comprehensively examines sleep among three distinct diagnostic groups of survivors in the SJLIFE cohort: ALL, CNS tumors, and non-CNS solid tumors. Primary Objective The primary aim of this protocol is to estimate the prevalence of various sleep disorders among long-term survivors of childhood ALL, CNS tumors, and non- CNS solid tumors. Exploratory Objective The exploratory objective of the study is to explore associations between the prevalence of sleep disorders and clinical outcomes collected in SJLIFE.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Participant in SJLIFE and \> 5 years from diagnosis.
* \>18 years of age at time of enrollment.
* Diagnosed with ALL (treated with CRT or chemotherapy only) or CNS tumors (posterior fossa tumors or supratentorial tumors) or non-CNS solid tumors (with abdominal or chest radiation or bilateral retinoblastoma survivors).
* Participant was less than 21 years of age at time of diagnosis.
* Speaks and understands English (polysomnography device speaks to patients only in English).
* Remote participant must have Wi-Fi access

Exclusion Criteria:

* Estimated intelligence score \<80.
* Currently prescribed an intervention for a sleep disorder.
* Survivor of craniopharyngioma.
* Survivor of Hodgkin Lymphoma.
* Relapsed or treated with hematopoietic stem cell therapy.
* Brain injury unrelated to cancer diagnosis or therapy.
* Pulmonary injury unrelated to cancer diagnosis or therapy.

Conditions4

ALL, AdultCNS TumorCancerSolid Tumor

Locations1 site

St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
Kevin Krull, PhD866-278-5833referralinfo@stjude.org

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