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Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin

RECRUITINGN/ASponsored by Case Comprehensive Cancer Center
Actively Recruiting
PhaseN/A
SponsorCase Comprehensive Cancer Center
Started2023-05-05
Est. completion2027-01-01
Eligibility
Age40 Years – 80 Years
Healthy vol.Accepted
Locations1 site

Summary

Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergistic effects of UWL detection and GRAIL usage to detect malignancy at an even earlier rate. UWL will be measured using weekly weight tracking.

Eligibility

Age: 40 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age range: from 40 to 80 years
* Access to a device (cellphone, computer, tablet) that is compatible with the Fitbit Aria Air smart scale utilized in this study
* Willing to comply with all study procedures and be available for the duration of the study
* Subjects must be mentally competent and must have the ability to understand and the willingness to sign a written informed consent document
* Subjects must speak English to maximize chance of understanding the trial rational and study procedures

Exclusion Criteria:

* Active cancer diagnosis - current diagnosis, currently undergoing cancer treatment, or concluded cancer treatments within 3 years
* Actively trying to lose weight with medications or bariatric surgery
* Pregnant

Conditions3

CancerUnintended Weight LossWeight Loss

Locations1 site

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106
Jordan M. Winter, MD216-844-5777Jordan.Winter@UHHospitals.org

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