Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

Summary

This study was designed to compare analgesic efficacy and safety of different perioperative analgesic modes in minimally invasive esophagectomy for esophageal cancer.

Eligibility

Inclusion Criteria:

* 18-75 years;
* Patients underwent laparoscopic and thoracoscopic or robotic-assisted minimally invasive esophagectomy ;
* Informed consent.

Exclusion Criteria:

* Has a history of cholecystitis or urolithiasis within 3 months;
* Has a history of atherothrombosis (peripheral arterial disease), stroke, myocardial infarction;
* With lung diseases, such as pneumonia, atelectasis, emphysema, pulmonary bullae, etc;
* Preoperative cardiac function grade ≥ III or coronary artery stenosis;
* Preoperative indwelling of a thoracic drainage tube;
* Long-term heavy drinker(heavy drinking was defined as follows: for men, consuming more than 4 drinks on any day or more than 14 drinks per week; For women, consuming more than 3 drinks on any day or more than 7 drinks per week);
* Opioid-tolerant patients(defined as those who have been taking, for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid);
* With painful skin complications, such as rashes and blisters;
* Conversion to open surgery;
* The postoperative ventilation function was limited, or the duration of endotracheal intubation was more than 24h.

Conditions6

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